Aspects of Common Marmoset Basic Biology and Life History Important for Biomedical Research
Abstract:While common marmosets are increasingly used as alternative primate models in biomedical research, their life history, specialized behavior and unique physiology are not well known. This paper describes important marmoset attributes that are particularly relevant for biomedical research, including reproduction, neurobiology, immunology, endocrine signaling, obesity and aging, in addition to fetal and postnatal development. While common marmosets exhibit characteristic anthropoid primate traits, they clearly differ from Old World primates and humans in a variety of functions, including reproduction, endocrine signaling and immunology. These differences, however, permit the use of common marmosets in unconventional research strategies targeted on human pathology.
Document Type: Research Article
Affiliations: 1: Wisconsin Primate Research Center, Department of Ob/Gyn, University of Wisconsin, 1223 Capitol Court, Madison, Wisconsin 53715 2: Wisconsin Primate Research Center, Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte, Natal, RN-Brasil
Publication date: August 1, 2003
Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.
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