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Open Access Detection of Infectious Agents in Laboratory Rodents: Traditional and Molecular Techniques

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Abstract:

Methods to detect infectious agents in laboratory animals have traditionally been serological and culture based. Molecular methods to detect infectious agents in laboratory animals are being used more routinely. Confusion as to when and how to use molecular methods abounds. In this review, we present a guide to the weaknesses and strengths of using traditional and molecular methods for the detection of infectious agents in laboratory animals.

Document Type: Research Article

Affiliations: 1: Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 2: Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri 65211

Publication date: April 1, 2001

More about this publication?
  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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